For the first time in Mid-East history, short-range Grads were used on Monday against advanced S-300 air defense systems. Both weapons are Russian-made. The attack by Syrian jihadist rebels targeted the three S-300 batteries securing the Syrian weapons center at Masyaf center overlooking the Mediterranean. The Grads missed their target. Russian and Syrian forces retaliated by shelling jihadist positions in southern Idlib. DEBKAfile’s military sources note that the Syrian “Scientific Studies and Research Center” at Masyaf hosts in addition to Iranian, Syrian and Hizballah officers, foreign missile experts who are helping the Syrian army develop high-precision missiles. Israel has conducted multiple air raids on the Masyaf center, most recently on April 13.